Allergies

New Research Shows Basophils Play Role In Allergic Reaction

A new research from the Yale University gives a new understanding of the allergic reaction – it shows that basophils play an important role triggering an allergic reaction. Until now, the role of basophils in the human immune response to allergic triggers was not properly understood. This research can open up better ways to treat allergies.

A team of Yale University scientists conducted this research to better understand how immune system identifies and reacts to the allergen. They found out that the current understanding  of the immune system response did not fully explain the allergic reaction.

The Study:

The scientists focused on basophils – a type of immune cells and their role in an allergic reaction. They found out that when an allergen is encountered, the basophils activate the T-cells to trigger an allergic reaction. The researchers were surprised to discover the role of basophils in the allergic reaction. Previously, it was thought that different immune cells known as dendritic cells were responsible for triggering an allergic reaction.

The scientists found at that the basophils were the first to signal to the immune system to fight the allergen and  trigger the allergic reaction. The basophils may also worsen the allergic reaction to the point where the symptoms would become extremely bothersome to the sufferer.

Presently treatments such as corticosteriods, ephiphrine,  immunotherapy etc. are available to treat an allergy reaction. This research can open new ways of treating an allergic reaction. Pharmaceutical therapies can better stop or decrease the allergic reaction if the allergy mechanism is properly understood.

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